Initially devised with the idea of disrupting a cancer-causing gene called BRD4, the new drug has also been found to inhibit proteins called bromodomains, one of which, BRDT, plays a key role in generating sperm in the testes. "If you stop the drug, there's complete reversibility," said Martin Matzuk, director of the Centre for Drug Discovery at Baylor College of Medicine in Houston, Texas.
Currently, male contraception is limited to the condom or vasectomy, so an easy-to-use reversible option is badly needed, iAfrica.com reports.
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